RESEARCH ARTICLE
Nobel Med 2020; 16(2): 47-54

THE EFFECT OF ENVIRONMENTAL ENRICHMENT AND WESTERN DIET ON THE TRACE ELEMENT STATUS AND OXIDATIVE STRESS IN RATS

Ümmügülsüm Can, Fatma Hümeyra Yerlikaya, Mehmet Oz, Kısmet Esra Nurullahoğlu Atalık, Hasan Serdar Gergerlioğlu
ABSTRACT
Objective:The Western diet (WD), which is rich in high-fat diet (HFD) and high-sucrose diet (HSD), is related to oxidative stress. Enriched environment (EE) with social interaction, physical exercise and continuous learning tasks has been shown to reduce oxidative stress, the inflammatory response, and increase the anti-oxidative defense. Therefore, the present study has aimed to clarify the effects of the EE and WD-fed rats on marker malondialdehyde (MDA) and trace element (TE) levels (iron [Fe], copper [Cu], zinc [Zn], chromium [Cr], selenium [Se], magnesium [Mg] and molybdenum [Mo]).

Material and Method: Male Wistar albino rats were housed in either an enrichment (n=24) or standard environment (n=24) and fed with HFD (35% of energy as fat) (n=8), HSD (100% of carbohydrate as sucrose) (n=8), or standard rat chow(n=8), for 4 weeks. Inductively-coupled plasma mass spectrometry was used for determination of the serum TE levels.

Results: The serum levels of MDA (p<0.05), Fe, Cu, Mo and Mg increased, while the serum levels of Cr and Se decreased, and additionally, the serum levels of Zn did not changed in the HFD and HSD groups. EE decreased partially the serum levels of MDA, Fe, Mo, and did not affect the serum levels of Cu, while it increased the serum levels of Mg, Cr, Se and Zn; however, there was no significant difference between all of the experimental groups (all; p>0.05).

Conclusions: Our study demonstrated that HFD and HSD led to oxidative stress and adversely affected the serum level of TE in rats, and that the EE reversed partially this status.
Keywords
Trace elements Western diet Malondialdehyde Oxidative stress

Authors Orcid Profiles

Ümmügülsüm Can
Fatma Hümeyra Yerlikaya
Mehmet Oz
Kısmet Esra Nurullahoğlu Atalık
Hasan Serdar Gergerlioğlu

Article Details

Download Full Text in PDF Format Read Full Text Other Articles in This Issue

A REVIEW ON THE ROLE OF ANGIOTENSIN II IN THE SKELETAL MUSCLE HYPERTROPHY AND MUSCLE STRENGTH

05-12

Andrei Ciobica, Alin Ciobica, Cezar Honceriu, Walther Bild

REVIEW Nobel Med 2020; 16(2): 5-12

EFFICACY OF PROJECT-WRITING AND APPLICATION TRAINING FOR ACADEMIC PERSONNEL IN THE FIELD OF HEALTH SCIENCES

13-22

Sibel Yalçın, Özgür Özerdoğan, Buse Yüksel, Coşkun Bakar

RESEARCH ARTICLE Nobel Med 2020; 16(2): 13-22

IMPORTANCE OF BERLIN, STOP, AND STOP-BANG QUESTIONNAIRES IN EVALUATING OBSTRUCTIVE SLEEP APNEA SYNDROME IN THE BUS DRIVERS

23-29

Nalan Eşrefoğlu, Ayşın Kısabay Ak, Tuğba Göktalay, Melike Batum, Hikmet Yılmaz

RESEARCH ARTICLE Nobel Med 2020; 16(2): 23-29

ERGONOMIC EVALUATION OF DESK-BOUND WORK OFFICES OF A COMMUNITY HEALTH CENTER AND EFFECT OF ERGONOMIC INTERVENTION ON THE HEALTH COMPLAINTS OF THE WORKERS

30-39

İsmail Hakkı Tunçez, Lütfi Saltuk Demir, Muammer Kunt, Tahir Kemal Şahin

RESEARCH ARTICLE Nobel Med 2020; 16(2): 30-39

CHANGES IN INTERPERSONAL RELATIONSHIPS OF PATIENTS WHO UNDERWENT OPEN HEART SURGERY

40-46

Gülcan Kendirkıran, Makbule Batmaz

RESEARCH ARTICLE Nobel Med 2020; 16(2): 40-46

THE EFFECT OF ENVIRONMENTAL ENRICHMENT AND WESTERN DIET ON THE TRACE ELEMENT STATUS AND OXIDATIVE STRESS IN RATS

47-54

Ümmügülsüm Can, Fatma Hümeyra Yerlikaya, Mehmet Oz, Kısmet Esra Nurullahoğlu Atalık, Hasan Serdar Gergerlioğlu

RESEARCH ARTICLE Nobel Med 2020; 16(2): 47-54

ORAL AND DENTAL HEALTH IN PREGNANCY: KNOWLEDGE OF GYNECOLOGISTS / OBSTETRICIANS, DENTISTS, FAMILY PHYSICIANS AND MIDWIVES

55-61

İrem Şenyuva, Cansu Koca

RESEARCH ARTICLE Nobel Med 2020; 16(2): 55-61

ASSESSMENT OF ‘PHYSICAL THERAPY FOR ELDERLY PEOPLE’ VIDEOS ON YOUTUBE

62-70

Özgür Özerdoğan, Tolgahan Kuru

RESEARCH ARTICLE Nobel Med 2020; 16(2): 62-70

PLATELET COUNTS OF THE INFANTS OF MOTHERS WHO HAD THROMBOCYTOPENIA DURING PREGNANCY

71-74

Özgül Bulut, Zeynep İnce, Asuman Çoban

RESEARCH ARTICLE Nobel Med 2020; 16(2): 71-74

EVALUATION OF ANTIBODY RESPONSE TO PNEUMOCOCCAL VACCINATION IN PATIENTS WITH INFLAMMATORY ARTHRITIS UNDER ANTI-TNF (ADALIMUMAB) TREATMENT

75-78

Hülya Çaşkurlu

RESEARCH ARTICLE Nobel Med 2020; 16(2): 75-78

PROF. DR. ORHAN NURİ ULUTİN (1924-2011) Hematoloji Alanında Dünyada Önde Gelen Bilim İnsanlarından

79-82

Emin Alkan

RESEARCH ARTICLE Nobel Med 2020; 16(2): 79-82

LIVER AND SYSTEMIC DISEASES

05-09

Sebati Özdemir

REVIEW Nobel Med 2013; 9(2): 5-9

AGING KIDNEY: SENESCENCE OR DISEASE?

10-14

Meltem Gürsu, Rümeyza Kazancıoğlu, Savaş Öztürk

REVIEW Nobel Med 2013; 9(2): 10-14

IMPORTANCE OF HOLOTRANSCOBALAMIN (HOLOTC) MEASUREMENTS IN EARLY DIAGNOSIS OF COBALAMIN DEFICIENCY, ESPECIALLY IN PATIENTS WITH BORDERLINE VITAMIN B12 CONCENTRATIONS

15-20

Faruk Sönmezışık, Esma Sürmen Gür, Burak Asıltaş

RESEARCH ARTICLE Nobel Med 2013; 9(2): 15-20

EVALUATION OF PHYSICAL GROWTH IN PATIENTS WITH FAMILIAL MEDITERRANEAN FEVER

21-25

Celalettin Koşan, Oğuzhan Sepetçigil, Atilla Çayır, Avni Kaya, Behzat Özkan

RESEARCH ARTICLE Nobel Med 2013; 9(2): 21-25

COMPARISON OF RISK INDEXES USED IN DETERMINING THE POSTOPERATIVE RESPIRATORY INSUFFICIENCY RISK

26-31

Gülsüm Kavalcı, Cavidan Arar, Alkın Çolak, Nesrin Turan, Cemil Kavalcı

RESEARCH ARTICLE Nobel Med 2013; 9(2): 26-31

THE EVALUATION OF PRENATAL AND ENVIROMENTAL RISK FACTORS IN CHILDREN WITH ASTHMA, ALLERGIC RHINITIS AND BRONCHIAL ASTHMA ABSTRACT

32-37

Mehmet İbrahim Turan, Müferet Ergüven, Mehmet Özdemir

RESEARCH ARTICLE Nobel Med 2013; 9(2): 32-37

REOPERATIONS AND MORBIDITY IN THYROID SURGERY

38-42

Serkan Teksöz, Murat Özcan, Aytül Sargan, Yusuf Bukey, Recep Özgültekin, Ateş Özyeğin

RESEARCH ARTICLE Nobel Med 2013; 9(2): 38-42

EFFECTS OF RAMADAN FASTING ON BLOOD PRESSURE CONTROL, LIPID PROFILE, BRAIN NATRIURETIC PEPTIDE, RENAL FUNCTIONS AND ELECTROLYTE LEVELS IN HYPERTENSIVE PATIENTS TAKING COMBINATION THERAPY

43-46

İbrahim Faruk Aktürk, İsmail Bıyık, Cüneyt Koşaş, Ahmet Arif Yalçın, Mehmet Ertürk, Fatih Uzun

RESEARCH ARTICLE Nobel Med 2013; 9(2): 43-46

MANAGEMENT OF A LARGE OUTBREAK CAUSED BY NOROVIRUS AND CAMPYLOBACTER JEJUNI OCCURRED IN A RURAL AREA IN TURKEY

47-51

İbak Gönen

RESEARCH ARTICLE Nobel Med 2013; 9(2): 47-51

FREQUENT CD99 AND FLI-1 EXPRESSIONS IN DIFFUSE LARGE B-CELL LYMPHOMA AND THEIR ASSOCIATION WITH PROLIFERATIVE AND APOPTOTIC RATES

52-56

Ufuk Berber, İsmail Yılmaz, Tolga Tuncel, Zafer Küçükodacı Aptullah Haholu

RESEARCH ARTICLE Nobel Med 2013; 9(2): 52-56
  • Pubmed Style
    Ümmügülsüm Can, Fatma Hümeyra Yerlikaya, Mehmet Oz, Kısmet Esra Nurullahoğlu Atalık, Hasan Serdar Gergerlioğlu. [THE EFFECT OF ENVIRONMENTAL ENRICHMENT AND WESTERN DIET ON THE TRACE ELEMENT STATUS AND OXIDATIVE STRESS IN RATS]. Nobel Med 2020; 16(2): 47-54, English.
  • Web Style
    Ümmügülsüm Can, Fatma Hümeyra Yerlikaya, Mehmet Oz, Kısmet Esra Nurullahoğlu Atalık, Hasan Serdar Gergerlioğlu. [THE EFFECT OF ENVIRONMENTAL ENRICHMENT AND WESTERN DIET ON THE TRACE ELEMENT STATUS AND OXIDATIVE STRESS IN RATS]. www.nobelmedicus.com/en/Article.aspx?m=1716 [Access: Mayıs 24, 2021], English.
  • AMA (American Medical Association) Style
    Ümmügülsüm Can, Fatma Hümeyra Yerlikaya, Mehmet Oz, Kısmet Esra Nurullahoğlu Atalık, Hasan Serdar Gergerlioğlu. [THE EFFECT OF ENVIRONMENTAL ENRICHMENT AND WESTERN DIET ON THE TRACE ELEMENT STATUS AND OXIDATIVE STRESS IN RATS]. Nobel Med 2020; 16(2): 47-54, English.
  • Vancouver/ICMJE Style
    Ümmügülsüm Can, Fatma Hümeyra Yerlikaya, Mehmet Oz, Kısmet Esra Nurullahoğlu Atalık, Hasan Serdar Gergerlioğlu. [THE EFFECT OF ENVIRONMENTAL ENRICHMENT AND WESTERN DIET ON THE TRACE ELEMENT STATUS AND OXIDATIVE STRESS IN RATS]. Nobel Med (2020); 16(2): 47-54, [cited Mayıs 24, 2021], English.
  • Harvard Style
    Ümmügülsüm Can, Fatma Hümeyra Yerlikaya, Mehmet Oz, Kısmet Esra Nurullahoğlu Atalık, Hasan Serdar Gergerlioğlu. (2020) [THE EFFECT OF ENVIRONMENTAL ENRICHMENT AND WESTERN DIET ON THE TRACE ELEMENT STATUS AND OXIDATIVE STRESS IN RATS]. Nobel Med, 16(2): 47-54, English.