Migraine is one of the most common neurological disorders and one of the most frequent cause of primary headaches. Migraine is often associated with functional impairment and leads to important costs with lost productivity. Various treatment strategies have been proposed to help clinicians providing the most effective acute treatment for migraine patients. Many medications have been used for acute treatment. Treatment is depends upon the severity and frequency of the migraine attacks. Among the medications that have been used as acute treatments for migraine are nonspecific agents, including non-steroidal anti-inflammatory drugs, analgesics (either single or combination), and narcotics, as well as migraine-specific medications, including ergot alkaloids and triptans (5-hydroxytryptamine 1B/1D agonists). All of these drugs have side effects that vary in type and severity. Each agent has its own distinct profile of efficacy and tolerability, enabling individualization of treatment. Therefore, consideration should be given to the tolerability and safety of medications before their use as abortive medications for the treatment of migraine headache. Clinical approaches to the patient with migraine attack include step care, whereby all patients begin on a simple or nonspecific treatment, stepping up to the next level of therapy if this treatment is unsuccessful. In this paper, we review to the options in the acute migraine treatment.

Migraine Acute attack treatment Triptans Non-steorid analgesics