REPORT
Nobel Med 2016; 12(3): 73-76

TUBERCULOSIS WITH ADRENAL INSUFFICIENCY MIMICKING MALIGNANCY IN FDG-PET IMAGES

Güzin Fidan Yaylalı, Olga Yaylalı, Doğangün Yüksel, Şenay Topsakal, Burhan Kabay, Neşe Dursunoğlu
ABSTRACT
Addison’s disease may result from adrenal tuberculosis (TB), malignancy, idiopathic adrenal atrophy, blastomycosis or histoplasmosis. Thus, adrenal masses are often characterized by fluorine-18 fluoro-2-deoxy-D-glucose positron emission tomography (18F FDG-PET), which identifies tumors by their increased glucose metabolism. However, a large number of clinical conditions lead to false positives in PET, often related to inflammation or infection. Herein, we present a patient with adrenal insufficiency associated with bilateral masses and a history of TB. We identified elevated FDG uptake in both adrenal glands that could not be differentiated from primary bilateral adrenal lymphoma or other malignancies. Following adrenalectomy, a final diagnosis of adrenal TB was made. This uncommon case emphasizes that benign adrenal lesions can have increased FDG uptake leading to false-positive results.
Keywords
Tuberculosis Adrenal insufficiency Malignancy FDG-PET Adrenal mass

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  • Pubmed Style
    Güzin Fidan Yaylalı, Olga Yaylalı, Doğangün Yüksel, Şenay Topsakal, Burhan Kabay, Neşe Dursunoğlu. [TUBERCULOSIS WITH ADRENAL INSUFFICIENCY MIMICKING MALIGNANCY IN FDG-PET IMAGES]. Nobel Med 2016; 12(3): 73-76, English.
  • Web Style
    Güzin Fidan Yaylalı, Olga Yaylalı, Doğangün Yüksel, Şenay Topsakal, Burhan Kabay, Neşe Dursunoğlu. [TUBERCULOSIS WITH ADRENAL INSUFFICIENCY MIMICKING MALIGNANCY IN FDG-PET IMAGES]. www.nobelmedicus.com/en/Article.aspx?m=1716 [Access: Mayıs 24, 2021], English.
  • AMA (American Medical Association) Style
    Güzin Fidan Yaylalı, Olga Yaylalı, Doğangün Yüksel, Şenay Topsakal, Burhan Kabay, Neşe Dursunoğlu. [TUBERCULOSIS WITH ADRENAL INSUFFICIENCY MIMICKING MALIGNANCY IN FDG-PET IMAGES]. Nobel Med 2016; 12(3): 73-76, English.
  • Vancouver/ICMJE Style
    Güzin Fidan Yaylalı, Olga Yaylalı, Doğangün Yüksel, Şenay Topsakal, Burhan Kabay, Neşe Dursunoğlu. [TUBERCULOSIS WITH ADRENAL INSUFFICIENCY MIMICKING MALIGNANCY IN FDG-PET IMAGES]. Nobel Med (2016); 12(3): 73-76, [cited Mayıs 24, 2021], English.
  • Harvard Style
    Güzin Fidan Yaylalı, Olga Yaylalı, Doğangün Yüksel, Şenay Topsakal, Burhan Kabay, Neşe Dursunoğlu. (2016) [TUBERCULOSIS WITH ADRENAL INSUFFICIENCY MIMICKING MALIGNANCY IN FDG-PET IMAGES]. Nobel Med, 12(3): 73-76, English.