THE INVESTIGATION OF ISOLATED HEPATIT B VIRUS CORE ANTIBODIES IN BLOOD DONORS

RESEARCH ARTICLE

Nobel Med 2009; 5(S1): 17-21

THE INVESTIGATION OF ISOLATED HEPATIT B VIRUS CORE ANTIBODIES IN BLOOD DONORS

Selçuk Kaya, Hasan Kesbiç, Güçhan Alanoğlu, Buket Cicioğlu Arıdoğan, Emel Sesli Çetin, Tekin Taş, Mustafa Demirci

ABSTRACT

In this study we aimed to determine the rate of Hepatitis B virus infection markers and the isolated anti-HBc positivity among blood donors. In addition, the HBV infectivity indicators are investigated in the isolated anti-HBc positive donors
2538 donors referring the Blood Bank of Hospital between february and may 2007 participated in the study. HBsAg was detected among 38 of the donors. The serum samples of the rest 2500 were assayed for anti-HBc total. 401 samples were found to display anti-HBc positivity, and all were tested for anti-HBs, HBeAg and anti-HBe.
At least one hepatitis B virus infection marker was detected to be positive among 17.3 % of blood donors in our region. 349 of 401 anti-HBc positive donors were anti-HBs positive, 11 (2.7%) HBeAg positive, and 125 (31.1%) were anti-HBe positive. 38 were only positive for anti-HBc, and negative for anti-HBs, anti-HBe and HBeAg.
In conclusion, although the rates of encountering the Hepatitis B virus among donors of our region was found lower than other parts of Turkey. The rate of 2 % for isolated anti-HBc positivity in blood donors emphasized the fact that isolated anti-HBc positive blood donors constitute a potential risk group for the transfer of HBV infection.

Keywords

Hepatitis B virus Isolated anti-HBc Donor

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Pubmed Style
Selçuk Kaya, Hasan Kesbiç, Güçhan Alanoğlu, Buket Cicioğlu Arıdoğan, Emel Sesli Çetin, Tekin Taş, Mustafa Demirci. [KAN DONÖRLERİNDE İZOLE HEPATİT B VİRUS CORE ANTİKORLARININ ARAŞTIRILMASI]. Nobel Med 2009; 5(S1): 17-21, Turkish.
Web Style
Selçuk Kaya, Hasan Kesbiç, Güçhan Alanoğlu, Buket Cicioğlu Arıdoğan, Emel Sesli Çetin, Tekin Taş, Mustafa Demirci. [KAN DONÖRLERİNDE İZOLE HEPATİT B VİRUS CORE ANTİKORLARININ ARAŞTIRILMASI]. www.nobelmedicus.com/en/Article.aspx?m=1716 [Access: Mayıs 24, 2021], Turkish.
AMA (American Medical Association) Style
Selçuk Kaya, Hasan Kesbiç, Güçhan Alanoğlu, Buket Cicioğlu Arıdoğan, Emel Sesli Çetin, Tekin Taş, Mustafa Demirci. [KAN DONÖRLERİNDE İZOLE HEPATİT B VİRUS CORE ANTİKORLARININ ARAŞTIRILMASI]. Nobel Med 2009; 5(S1): 17-21, Turkish.
Vancouver/ICMJE Style
Selçuk Kaya, Hasan Kesbiç, Güçhan Alanoğlu, Buket Cicioğlu Arıdoğan, Emel Sesli Çetin, Tekin Taş, Mustafa Demirci. [KAN DONÖRLERİNDE İZOLE HEPATİT B VİRUS CORE ANTİKORLARININ ARAŞTIRILMASI]. Nobel Med (2009); 5(S1): 17-21, [cited Mayıs 24, 2021], Turkish.
Harvard Style
Selçuk Kaya, Hasan Kesbiç, Güçhan Alanoğlu, Buket Cicioğlu Arıdoğan, Emel Sesli Çetin, Tekin Taş, Mustafa Demirci. (2009) [KAN DONÖRLERİNDE İZOLE HEPATİT B VİRUS CORE ANTİKORLARININ ARAŞTIRILMASI]. Nobel Med, 5(S1): 17-21, Turkish.