REPORT
Nobel Med 2008; 4(1): 28-30

A CASE REPORT OF BONE MARROW SUPPRESSION CAUSED BY PIPERACILLIN TAZOBACTAM

Ahmet Ekmekçi, Fatih Yakar, Fatih Tufan, Mustafa Demirtürk, Atahan Çağatay
ABSTRACT
Piperacillin/tazobactam (PT) is a commonly prescribed antibiotic and is generally considered safe. During treatment with piperacillin/tazobactam bone marrow suppression can rarely be seen as a serious adverse effect. We report here a case of PT induced bone marrow suppression. A 58 year old man was being treated with PT for empyema. After 20 days of treatment, he developed neutropenia and thrombocytopenia.

The findings reversed promptly after cessation of PT. The time of course of events suggested that PT was the cause of bone marrow suppression in this patient.
Keywords
Piperacillin Tazobactam Bone marrow suppression Neutropenia Thrombocytopenia

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  • Pubmed Style
    Ahmet Ekmekçi, Fatih Yakar, Fatih Tufan, Mustafa Demirtürk, Atahan Çağatay. [PİPERASİLİN/TAZOBAKTAMA BAĞLI KEMİK İLİĞİ BASKILANMASI İLE SEYREDEN BİR OLGU SUNUMU ]. Nobel Med 2008; 4(1): 28-30, Turkish.
  • Web Style
    Ahmet Ekmekçi, Fatih Yakar, Fatih Tufan, Mustafa Demirtürk, Atahan Çağatay. [PİPERASİLİN/TAZOBAKTAMA BAĞLI KEMİK İLİĞİ BASKILANMASI İLE SEYREDEN BİR OLGU SUNUMU ]. www.nobelmedicus.com/en/Article.aspx?m=1716 [Access: Mayıs 24, 2021], Turkish.
  • AMA (American Medical Association) Style
    Ahmet Ekmekçi, Fatih Yakar, Fatih Tufan, Mustafa Demirtürk, Atahan Çağatay. [PİPERASİLİN/TAZOBAKTAMA BAĞLI KEMİK İLİĞİ BASKILANMASI İLE SEYREDEN BİR OLGU SUNUMU ]. Nobel Med 2008; 4(1): 28-30, Turkish.
  • Vancouver/ICMJE Style
    Ahmet Ekmekçi, Fatih Yakar, Fatih Tufan, Mustafa Demirtürk, Atahan Çağatay. [PİPERASİLİN/TAZOBAKTAMA BAĞLI KEMİK İLİĞİ BASKILANMASI İLE SEYREDEN BİR OLGU SUNUMU ]. Nobel Med (2008); 4(1): 28-30, [cited Mayıs 24, 2021], Turkish.
  • Harvard Style
    Ahmet Ekmekçi, Fatih Yakar, Fatih Tufan, Mustafa Demirtürk, Atahan Çağatay. (2008) [PİPERASİLİN/TAZOBAKTAMA BAĞLI KEMİK İLİĞİ BASKILANMASI İLE SEYREDEN BİR OLGU SUNUMU ]. Nobel Med, 4(1): 28-30, Turkish.