REPORT
Nobel Med 2012; 8(1): 110-113

THE PERIODONTAL MANAGEMENT OF A PATIENT WITH ACUTE MYELOMONOCYTIC LEUKEMIA

Esra Güzeldemir, Hilal Uslu Toygar, Nazım Emrah Koçer, Ebru Kızılkılıç
ABSTRACT
Acute myelomonocytic leukemia (AML) is a malignant-hematopoetic clonal disease of bone marrow and impaired production of normal blood cells. The leukemic cell infiltration may be companied by anemia and thrombocytopenia. Oral manifestations of the disease are gingival ulcerations, mucositis, gingival bleeding and gingival enlargement. A 47-year-old-man with AML-M4 referred to periodontology clinic for treatment of gingival hyperplasia and bleeding. At the second appointment, diffuse gingival ulcerations were seen. Two teeth were extracted under antibiotic prophylaxis. Gingival specimens were sent to pathology. Histochemical/immunohistochemical analysis showed AML. His medical therapy continued with chemotherapy and allogeneic bone marrow transplantation. He died 9 months after initial diagnosis.

This case report represents not only manifestations of AML such as gingival hyperplasia, ulcerations and bleeding, but also reflects the acute course of the disease in the oral cavity. Dental consultation is essential for diagnosis and improvement of medical conditions. Systemic diseases are not obstacles for dental/periodontal procedures under the proper circumstances.
Keywords
Acute myeloid leukemia Gingival hyperplasia Chemotherapy Oral manifestations

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  • Pubmed Style
    Esra Güzeldemir, Hilal Uslu Toygar, Nazım Emrah Koçer, Ebru Kızılkılıç. [THE PERIODONTAL MANAGEMENT OF A PATIENT WITH ACUTE MYELOMONOCYTIC LEUKEMIA]. Nobel Med 2012; 8(1): 110-113, English.
  • Web Style
    Esra Güzeldemir, Hilal Uslu Toygar, Nazım Emrah Koçer, Ebru Kızılkılıç. [THE PERIODONTAL MANAGEMENT OF A PATIENT WITH ACUTE MYELOMONOCYTIC LEUKEMIA]. www.nobelmedicus.com/en/Article.aspx?m=1716 [Access: Mayıs 24, 2021], English.
  • AMA (American Medical Association) Style
    Esra Güzeldemir, Hilal Uslu Toygar, Nazım Emrah Koçer, Ebru Kızılkılıç. [THE PERIODONTAL MANAGEMENT OF A PATIENT WITH ACUTE MYELOMONOCYTIC LEUKEMIA]. Nobel Med 2012; 8(1): 110-113, English.
  • Vancouver/ICMJE Style
    Esra Güzeldemir, Hilal Uslu Toygar, Nazım Emrah Koçer, Ebru Kızılkılıç. [THE PERIODONTAL MANAGEMENT OF A PATIENT WITH ACUTE MYELOMONOCYTIC LEUKEMIA]. Nobel Med (2012); 8(1): 110-113, [cited Mayıs 24, 2021], English.
  • Harvard Style
    Esra Güzeldemir, Hilal Uslu Toygar, Nazım Emrah Koçer, Ebru Kızılkılıç. (2012) [THE PERIODONTAL MANAGEMENT OF A PATIENT WITH ACUTE MYELOMONOCYTIC LEUKEMIA]. Nobel Med, 8(1): 110-113, English.