RESEARCH ARTICLE
Nobel Med 2008; 4(3): 32-36
THE MEANING OF INCREASED CA125 IN INTERNAL MEDICINE PRACTICE
Gülistan Bahat, Fulya Coşan, Bulent Saka, Sami Uzun, Savaş Özturk, Nilgün Erten, Mehmet Akif Karan, Cemil TaşçıoğluABSTRACT
Patients and methods: A total of 420 CA125 assays were prospectively analysed between March 2003 and October 2003 in Istanbul University, Internal Medicine Department. Clinical diagnosis, presence of any serosal effusion, age and sex were evaluated.
Results: 103 (24.5%) patients had a value of CA125 >35 kU/L. 60 were women and 43 were men. Their median age was 63 years (range, 15-92 years). Benign causes were slightly more frequent than malignant ones. The most frequent diagnosis was hematological malignancy (25.2%). In this group, there was significant superiority of non-Hodgkin's lymphoma (13 patients; 50%). Effusions were found in 48 patients (46.6%). All the 3 patients with CA125>1000 kU/L had a metastatic solid malignancy.
Conclusion: Our study suggests that pathologies causing increase in CA125 is quite frequent in internal medicine practice. In any patient with an increased CA125 level, these common pathologies documented in our study should be considered. Very high levels of CA125 are more commonly associated with a malignancy.
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Pubmed Style
Gülistan Bahat, Fulya Coşan, Bulent Saka, Sami Uzun, Savaş Özturk, Nilgün Erten, Mehmet Akif Karan, Cemil Taşçıoğlu. [THE MEANING OF INCREASED CA125 IN INTERNAL MEDICINE PRACTICE]. Nobel Med 2008; 4(3): 32-36, English. -
Web Style
Gülistan Bahat, Fulya Coşan, Bulent Saka, Sami Uzun, Savaş Özturk, Nilgün Erten, Mehmet Akif Karan, Cemil Taşçıoğlu. [THE MEANING OF INCREASED CA125 IN INTERNAL MEDICINE PRACTICE]. www.nobelmedicus.com/en/Article.aspx?m=1716 [Access: Mayıs 24, 2021], English. -
AMA (American Medical Association) Style
Gülistan Bahat, Fulya Coşan, Bulent Saka, Sami Uzun, Savaş Özturk, Nilgün Erten, Mehmet Akif Karan, Cemil Taşçıoğlu. [THE MEANING OF INCREASED CA125 IN INTERNAL MEDICINE PRACTICE]. Nobel Med 2008; 4(3): 32-36, English. -
Vancouver/ICMJE Style
Gülistan Bahat, Fulya Coşan, Bulent Saka, Sami Uzun, Savaş Özturk, Nilgün Erten, Mehmet Akif Karan, Cemil Taşçıoğlu. [THE MEANING OF INCREASED CA125 IN INTERNAL MEDICINE PRACTICE]. Nobel Med (2008); 4(3): 32-36, [cited Mayıs 24, 2021], English. -
Harvard Style
Gülistan Bahat, Fulya Coşan, Bulent Saka, Sami Uzun, Savaş Özturk, Nilgün Erten, Mehmet Akif Karan, Cemil Taşçıoğlu. (2008) [THE MEANING OF INCREASED CA125 IN INTERNAL MEDICINE PRACTICE]. Nobel Med, 4(3): 32-36, English.