REPORT
Nobel Med 2008; 4(2): 33-35

A RARE CASE OF TIBOLONE INDUCED TOXIC HEPATITIS

Erkan Cüre, Kasım Demir, Cem Koçkar, Abdülkadir Baştürk, Altuğ Şenol
ABSTRACT
Tibolone is a synthetic steroid with estrogenic, androgenic and progestogenic properties used primarily for the treatment of menopausal symptoms. Tibolone may rarely cause hepatotoxicity. Here, we report tibolone induced hepatotoxicity.
A 52 year-old woman was admitted to our hospital with a complaint of abdominal pain. Her hepatic function tests were found to be elevated. Impairment of liver function tests was thought to be caused by using tibolone, and tibolone was stopped. During follow up, her liver function tests were normalized in fifteen months.

It is known that drug induced hepatotoxicity is usually normalized in 3 months to 1 year. But it should be kept in mind that normalization of hepatotoxicity may rarely prolong to more than one year as in this case.
Keywords
Tibolone Hepatotoxicity Toxic hepatitis

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  • Pubmed Style
    Erkan Cüre, Kasım Demir, Cem Koçkar, Abdülkadir Baştürk, Altuğ Şenol. [A RARE CASE OF TIBOLONE INDUCED TOXIC HEPATITIS]. Nobel Med 2008; 4(2): 33-35, English.
  • Web Style
    Erkan Cüre, Kasım Demir, Cem Koçkar, Abdülkadir Baştürk, Altuğ Şenol. [A RARE CASE OF TIBOLONE INDUCED TOXIC HEPATITIS]. www.nobelmedicus.com/en/Article.aspx?m=1716 [Access: Mayıs 24, 2021], English.
  • AMA (American Medical Association) Style
    Erkan Cüre, Kasım Demir, Cem Koçkar, Abdülkadir Baştürk, Altuğ Şenol. [A RARE CASE OF TIBOLONE INDUCED TOXIC HEPATITIS]. Nobel Med 2008; 4(2): 33-35, English.
  • Vancouver/ICMJE Style
    Erkan Cüre, Kasım Demir, Cem Koçkar, Abdülkadir Baştürk, Altuğ Şenol. [A RARE CASE OF TIBOLONE INDUCED TOXIC HEPATITIS]. Nobel Med (2008); 4(2): 33-35, [cited Mayıs 24, 2021], English.
  • Harvard Style
    Erkan Cüre, Kasım Demir, Cem Koçkar, Abdülkadir Baştürk, Altuğ Şenol. (2008) [A RARE CASE OF TIBOLONE INDUCED TOXIC HEPATITIS]. Nobel Med, 4(2): 33-35, English.